Conolidine’s analgesic consequences stem from its interaction with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors while in the central nervous method, conolidine modulates alternate molecular targets. A Science Advancements review found that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. https://travisfboye.pages10.com/the-2-minute-rule-for-conolidin-to-replace-traditional-painkillers-73117894