Lyme disease which has been highly publicized since its outbreak in the 1970's.
Force on muscles and joints, from activities while sports, along with other activities of daily living as well as mental stress will result in misalignment belonging to the spine and muscle spasms. https://medium.com/@cbdsupplements_15259/the-secret-to-muscle-recovery-cbd-supplements-8c4ff1e4b6fb